Trichostatin A Extends the Lifespan of Drosophila melanogaster by Elevating hsp22 Expression
نویسندگان
چکیده
منابع مشابه
Reduced expression of alpha-1,2-mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans.
Exposure to sub-lethal levels of stress, or hormesis, was a means to induce longevity. By screening for mutations that enhance resistance to multiple stresses, we identified multiple alleles of alpha-1,2-mannosidase I (mas1) which, in addition to promoting stress resistance, also extended longevity. Longevity enhancement is also observed when mas1 expression is reduced via RNA interference in b...
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2004
ISSN: 1745-7270
DOI: 10.1093/abbs/36.9.618